Buffalo Bills vs Cincinnati Bengals Betting Odds, AI Picks and Analysis

There are some huge games on the schedule during Week 9 of the NFL season, including the Buffalo Bills visiting the Cincinnati Bengals. There are some interesting Bills vs Bengals betting lines set for this matchup, and that will create some good bets to make.
The league tries to do a great job of setting up some big games for primetime, and this Bills vs Bengals betting game definitely falls into that category. These are two of the best teams in the AFC this season, and they could end up playing again in the postseason.
Game Information
BUFFALO BILLS vs CINCINNATI BENGALS |
Location of the Game: Paycor Stadium, Cincinnati, OH |
Date and Time: Sunday, November 5, 8:20 PM ET |
Reason: NFL Week 9 Regular Season Matchup |
How to watch: NBC |

AI Predictions and SportBettingAI Picks
Here are the AI Picks and Predictions for the Bills vs Bengals Betting Game
TEAM | RECORD | AI PICKS | SportBettingAI PICKS | |||
BILLS | 5-3 | 24 | 51 |
SPREAD CIN -2.0 |
MONEYLINE CIN -130 |
TOTAL OVER 49.5 (-110) |
BENGALS | 4-3 | 27 |
Bills vs Bengals Betting Odds
Here is a look at some of the best Bills vs Bengals betting odds that you are going to see for this matchup on Sunday Night Football.
TEAM | POINT SPREAD | MONEYLINE | OVER/UNDER | TEAM TOTAL |
Bills | +2.0 | +110 | O 49.5 (-110 | O/U 24.5 |
Bengals | -2.0 | -130 | U 49.5 (-110) | O/U 25.5 |
Buffalo Bills Game Analysis

The Buffalo Bills roster has a ton of postseason success, but they don’t always focus on the regular season games. There is a reason that the Bills are just 5-3 on the year as they have dropped some games that they should have won.
Buffalo quarterback Josh Allen has been able to avoid NFL injuries over the last few years and he continues to be an MVP candidate. Allen has thrown for 17 touchdowns this season, but he has also turned the ball over eight times.
The defense of Buffalo is going to be tested in a big way in this game, and that unit has to prove that it can stand tall. Buffalo has struggled to get stops in their losses this year, and that simply can’t happen in this game.
Playing on the road will impact the offensive play calling a bit for the Bills, but they will still try to get the football to Stefon Diggs when possible. Diggs has 64 receptions for 748 yards and six touchdowns this season.
Cincinnati Bengals Game Analysis

The Cincinnati Bengals have been climbing up the NFL standings of late, but they got off to a miserable start to the season. Cincinnati is now sitting at 4-3 on the year, but it has taken three straight wins in order to get to that point.
The Cincinnati Bengals standings are really determined by how well this offense plays, and quarterback Joe Burrow is the leader of this team. Burrow has thrown for just 1,513 yards and 10 touchdowns this season, but he has been getting better.
Burrow is typically looking for Ja’Marr Chase when he is throwing the football, and those two have connected 60 times this season. Running the football continues to be an issue for the Bengals as Joe Mixon has just 453 yards and two touchdowns.
The Bengals’ defense has helped to lead the charge over the last few years, but getting stops against Josh Allen isn’t going to be easy.
Buffalo Bills vs. Cincinnati Bengals Head-to-Head
Looking at the NFL standings this year is important when breaking down a game, and for the Bills vs Bengals betting, you also want to look at history in head-to-head matchups. This will be the 34th all-time meeting between the Bills and Bengals, and they have played in some battles.
Buffalo is coming into this game having won 17 of the 33 previous matchups against Cincinnati. These two teams have been battling of late as well as they have split the last six games, with the Bengals picking up a 27-10 win in the most recent game. There is an important stat for the Bills vs Bengals Betting.
One look at the Bills vs Bengals betting odds for Sunday Night Football shows just how tight this game might be, and it should be a battle for four quarters. There are some great NFL teams playing on Sunday in Week 9, but this will be the perfect game to round things out.