SSC Napoli vs FC Barcelona Prediction Odds, AI Picks and Betting Analysis

A standout tie on the UCL schedule will be staged in Naples on Wednesday, as the reigning champions of Italy and Spain collide in the round of 16. There will be pressure on both Barcelona and Napoli after their title defenses have fallen flat, meaning that the Champions League could present them with their best chance of a major honor this term.
It could be a fascinating opening leg of this Napoli vs Barcelona matchup, with both sides making interesting cases. But, you can find the latest UCL odds and our Napoli vs Barcelona prediction here.
Game Information
SSC NAPOLI vs FC BARCELONA |
Location of the Game: Stadio Diego Armando Maradona, Naples, Italy |
Date and Time: Wednesday, February 21, 2024. 3:00 PM ET |
Reason: 2023-2024 UEFA Champions League Round of 16 |
How to watch: CBS |
Napoli vs Barcelona Pick and Prediction
ODDS | AI PICKS |
MONEYLINE | Draw +247 |
It could be testing to make a Napoli vs Barcelona prediction this week based on a number of trends that both sides need to overcome. Napoli haven’t previously claimed victory in four European matches against their Spanish rivals, while Barcelona are winless in their last three against sides from Italy.
Furthermore, the La Liga champions come into this round of UCL matchups after winning just once in their last ten away matches in the knockout stage of the competition. Therefore, one of the most interesting UCL computer picks this week could be the draw.
Napoli vs Barcelona Prediction Odds
TEAM | RECORD | MONEYLINE | HANDICAP | OVER/UNDER |
NAPOLI | 3-1-2 10Pts | +179 | PK | O 2.5 |
BARCELONA | 4-0-2 12Pts | +150 | PK | U 2.5 |
DRAW | +247 |
An away win will rank among the prominent picks at +150 when making a Napoli vs Barcelona prediction. A home victory for Napoli is priced up at +179, while the draw is the eye-catching selection at +247.
Napoli vs Barcelona Analysis
Napoli Preview
The pressure will be on the home side for this first leg in the round of 16. Napoli comes into the knockout stage after winning three of their six matches in the Champions League this term, finishing second in the UCL standings behind Real Madrid.
The Italian champions were beaten in both matches by the Spanish giants, which included a thrilling 3-2 home defeat in Naples. However, Napoli were much the best of the remainder, landing wins against Braga and Union Berlin.
But, their home form remains one of the most concerning Napoli stats this term. They only won once in three European matches in Naples, while they have picked up just four victories from eleven domestic home matches in Serie A this term.
However, the UCL team stats show that they have an excellent attacking record after netting ten in six matches before Christmas. That includes five in their three home matches in the group stage.
Barcelona Preview
It would be fair to say that Barcelona aren’t the force of old in Europe, but they still have a lot of quality across the field to suggest that they could make a charge to latter stages of the Champions League this term.
Xavi’s side were extremely fortunate to finish top of the Group H standings, despite finishing with a worse goal difference than second-place Porto. However, their two victories over the eventual runners-up were the key Barcelona scores.
The Spanish giants weren’t great on the road in the opening round, suffering defeats against both Shakhtar Donetsk and Royal Antwerp. That record remains a key concern when it comes to betting on this fixture in Naples.
However, they have no fresh UCL injuries to address, and they boast one of the leading forwards based on UCL player stats. Robert Lewandowski could be a key player in the final third after having already netted 16 goals across all competitions this term.
Napoli vs Barcelona Head to Head
Barcelona have picked up two victories from their four matches against Napoli, with the remaining two clashes ending in draws. The Spanish giants landed a 4-2 success in the previous meeting between the sides in the playoff round of the Europa League in 2021-22.
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