Detroit Lions vs San Francisco 49ers Betting Odds, AI Picks and Analysis

Looking at the NFC-North standings, the Lions are in 1st place on a record of 12-5. In the NFC, Detroit is in 3rd place heading into the Conference Championship. The Lions’ scoring margin thus far is currently at +3.9. This has contributed to an ATS record of 13-6.
The 49ers come into their matchup against the Lions with a 12-5 record. In the NFC-West, they are 1st and 1st in NFC overall NFL standings. Looking at their ATS performance so far, the 49ers are above .500 at 9-8-1. Their average scoring margin is +10.9.
Game Information
DETROIT LIONS vs SAN FRANCISCO 49ERS |
Location of the Game: Levi’s Stadium, Santa Clara |
Date and Time: Sunday, January 28th 6:30 ET |
Season: 2023-2024 NFC Championship Game |
How to watch: watchlivesports.co |
AI Predictions and Sport BettingAI Picks
Here are the NFL Computer Picks for Lions vs 49ers Betting Odds matchup.
TEAM | RECORD | AI PICKS | Sport Betting AI PICKS | |||
LIONS | 12-5 | 23 | 51 | Spread DET +7 |
ML SF -333 |
Total U 51 |
49ERS | 12-5 | 28 |
AI Picks: San Francisco 49ers 28 – Detroit Lions 23
Sport Betting AI Picks: ATS Lions +7 | ML 49ers -333 | UNDER 51
Lions vs 49ers Betting Odds
These are the NFL odds for this Matchup for the NFL Playoffs
Detroit Lions Game Analysis
In the Lions’ 31-23 win over the Buccaneers, the two teams were all tied at 10 at halftime. For the game, the Detroit Lions went 6/14 on third down and allowed the Buccaneers to convert 33.3% of their third downs. The Lions finished with 391 of total offense. Going into the game, Detroit was favored by 6.5 and went on to cover the spread. Jared Goff threw for 287 yards while completing 69% of his passes and throwing for 287. Goff threw for two touchdowns.
Quarterback Jared Goff leads the league’s 5th-ranked scoring offense into San Francisco, averaging 259.6 passing yards per game in their NFL player stats. Detroit will continue turning to the pass on offense, as they throw the ball an average of 35.6 times per contest. Overall, Goff has put together a passer rating of 97.9 while throwing for 4575 yards. The team’s top receiver Amon-Ra St. Brown, has caught 119 passes and has accumulated 1515 receiving yards this season.
San Francisco 49ers Game Analysis
Despite a scoreless first quarter, the San Francisco 49ers managed to bounce back and secure the win. On the offensive front, they accumulated 356 yards, while allowing 330 yards to the Packers. Even though San Francisco won straight-up, they did not cover the spread as 10.5-point favorites. Brock Purdy threw for 252 yards while completing 59% of his passes and throwing for 252. Purdy threw for one touchdown.
San Francisco is looking to continue with their efficient play in the passing game, as they are just 28th in the league in passing attempts but are still averaging 257.2 yards per game. Overall, in the NFL team stats, the team is scoring at a rate of 28.6 points per contest. At the quarterback position, Brock Purdy enters play as the 5th ranked QB in passing yards, with total of 4280. The team’s top receiver Brandon Aiyuk, has caught 75 passes and has accumulated 1342 receiving yards this season.
NFL Injury Report
For this NFL schedule, there is the NFL Injury Report for both teams:
Detroit Lions
- Khalil Dorsey – Illness (Out)
- Julian Okwara – Arm (Out)
- David Montgomery – Thigh (Out)
- C.J. Gardner-Johnson – Pectoral (Out)
- Emmanuel Moseley – Knee/hamstring (Out)
- Taylor Decker – Ankle (Out)
- Nate Sudfeld – Knee (Out)
- Halapoulivaati Vaitai – Knee (Out)
- Shane Zylstra – Knee (Out)
- Jameson Williams – Suspension (Out)
- James Houston – Ankle (Out)
- Josh Paschal – Knee (Out)
- Kerby Joseph – Hip (Out)
- Hendon Hooker – Knee (Out)
San Francisco 49ers
- Brandon Aiyuk – Shoulder (Out)
- Danny Gray – Shoulder (Out)
- Samuel Womack III – Knee (Out)
- Ambry Thomas – Knee (Out)
- Robert Beal Jr. – Hamstring (Out)
- Cameron Latu – Knee (Out)
- Darrell Luter Jr. – Knee (Out)
Detroit Lions vs San Francisco 49ers Head-to-Head
The last ten head-to-head matchups between then 49ers and Lions have gone in favor of the 49ers, putting together a record of 9-1. When looking at the last three head-to-head matchups between the Lions and 49ers, only 1 point per game has separated the teams, with the Lions going 3-0 vs. the spread. Going back to the last five head-to-head games between the 49ers and Lions, the over/under record in these games is 3-2 with a combined average of 54 points per contest.
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