Washington Huskies vs USC Trojans Odds, AI Picks, and AI Prediction

The Pac-12 Conference is loaded with great teams this season, and two of them will be meeting up in Week 10. The Washington Huskies visit the USC Trojans on Saturday night, and this Washington vs USC betting match should be one of the best games of the weekend.
Not only will this game be a great game to watch, but you are also going to see some great betting options in this game. Here is a look at some Washington vs USC betting analysis that will help you make some picks and predictions for this game.
Game Information
WASHINGTON HUSKIES vs USC TROJANS |
Location of the Game: Los Angeles Memorial Coliseum, Los Angeles, CA |
Date and Time: Saturday, November 4, 7:30 PM ET |
Reason: 2023 College Football Regular Season Week 10 |
How to watch: ABC |

Washington vs USC Betting Odds
If you are going to make some Washington vs USC betting picks on Saturday night then you first want to look at the odds that are available. The NCAAF odds for this game have the Huskies as slim three-point betting favorites, and that spread might actually seem too small.
For this Washington vs USC betting game, you can also look at making NCAAF picks on the point total in this game and that over/under line is set at 76.5 points. It’s very unusual to see an over/under line set at that many points, but both of these offenses are terrific.
Betting Preview
Penix Making Plays For Huskies

This Washington roster is loaded with some great players, but it’s quarterback Micchael Penix Jr. who is the best player on this team. Penix has thrown for 2,945 yards and 24 touchdowns this season, and he is currently the betting favorite to win the Heisman Trophy.
There are so many weapons on offense for Washington, and they have scored a ton of points this season. Many tend to focus on the Huskies’ passing attack, but this team is also able to make some plays on the ground as well.
This Washington defense has also been getting the job done of late, and getting pressure on Calabe Williams is going to be a huge key in this matchup. Washington has a terrific secondary, but it will be the defensive front that stands tall in this matchup.
The Huskies are at the top of the NCAAF standings in the Pac-12 at the moment, but they can be caught if they suffer a loss.
Trojans Have to Get Stops

It hasn’t been easy to make a USC Trojans prediction this season as they have been incredibly inconsistent. Even in some games that USC has won this season, they have struggled to take care of some of the worst teams in the Pac-12 Conference.
USC has allowed at least 34 points in five straight weeks and there is a ton of pressure on this defense to deliver. The secondary of the Trojans has been a major issue all season long, and that could be a huge problem against Penix and the Huskies’ offense.
Quarterback Caleb Williams is good enough to win games on his own, but he has had to do that in most games this season. Williams has thrown for 2,646 yards and 25 touchdowns this season, but he just isn’t getting a ton of help.
Running back Marshawn Lloyd can give Williams some support in this game as he is averaging 7.7 yards per carry. USC will need to find some balance on offense if they want to win this game.
AI Betting Picks
ODDS | AI BETTING PICKS |
OVER/UNDER | UNDER 76.5 |
SPREAD | Washington Huskies -3.0 |
For the Washington vs USC betting odds, there aren’t really any significant NCAAF injuries to worry about in this game, and that’s going to allow all the best players to be on the field in this one. This is a tough game on the NCAAF schedule for Washington, but they have won some big games already this season.
Both of these teams might be terrific on offense this season, but it’s not like there won’t be a defense on the field in this game. If you are going to make a Washington vs USC betting pick on the point total in this game then you simply have to take the under.
In summary, for this Washington vs USC betting game, the USC is going to battle for four quarters in this game, but they are going to come up short in the upset bid. Not only does Washington win this game, but they are going to cover the spread as well.
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